Discovery of Highly Potent Benzimidazole Derivatives as Indoleamine 2,3-Dioxygenase-1 (IDO1) Inhibitors: From Structure-Based Virtual Screening to in Vivo Pharmacodynamic Activity.
2020
In this study, a successful medicinal chemistry campaign that exploited virtual, biophysical and biological investigations led to the identification of a novel class of IDO1 inhibitors based on a b...
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