CT guided 125I implantation in treatment of salivary gland carcinoma with lung metastasis

Objective To evaluate the curative effect of CT guided percutaneous puncture of radioactive 125I seeds in treatment of salivary gland carcinoma with lung metastasis. Methods 18 patients with 42 salivary gland carcinoma of the lung metastases, received CT-guided percutaneous puncture of 125I radioactive particles. No other treatment was given. The prescription dose was 80 Gy. Results After six months, CT showed that the tumor complete remission (CR) rate was 28.6%, (12/42) , partial response (PR) 57.1% (24/42) , stable disease (SD) 9.5% (4/42) , progressive disease (PD) 4.8% (2/42) , and the total effective rate 85.7% (36/42) . 16 cases survived within 1 year (88.9%) , 12 cases in 2 years (66.7%) , and 9 cases in 3 years (50%) . Conclusion CT guided percutaneous puncture of radioactive 125I particles has recent efficacy in treatment of salivary gland carcinoma with lung metastasis in the future. Key words: Adenocarcinoma of salivary gland; Pulmonary metastasis; 125I; CT