Performance of Composite Cements in the Repair of Porcine Thoracolumbar Burst Fracture In Vitro

An ideal injectable bone cement should be able to fill fully the fractures gap and provide good mechanical support. In the present work, the mineralized collagen and calcium sulphate dehydrate (CSD) was incorporated into α-calcium sulphate hemihydrates (α-CSH) to explore an injectable composite cement. The injectability, the setting time and the biomechanics properties were investigated. A porcine thoracolumbar burst fracture model was used to evaluate the biomechanical performance of composite cements. The porcine thoracolumbar burst fracture models in vitro were prepared. A half of models was made by the vertebroplasty of the composite cements, the other half of models was used as control. Imaging analysis showed the composite cements distributed uniformly and solidified well. Biomechanical test showed the ability of the composite cements to repair spinal burst fractures was significant.