Estudio etnobotánico y evaluación citotóxica de extractos etanólicos de plantas de uso medicinal en Tlalchi, Ixhuacán de los Reyes, Veracruz, México

Medicinal plants are species that contain substances used for therapeutic purposes and can serve as precursors for the synthesis of new drugs. In the present work, an ethnobotanical and toxicological study of medicinal plants of greater importance was carried out in the town of Tlalchi, Ixhuacan de los Reyes in the state of Veracruz, Mexico. 22 species were registered distributed in 17 families, highlighting  Asteraceae  with  the  highest  frequency  number.  The  selected  species  were  Solanum nigrum,  Bidens  pilosa,  Tithonia  diversifolia,  Commelina  diffusa,  Justicia  pectoralis  and  Aldama dentata, them have the presence of alkaloids, flavonoids, triterpenes and saponins. Solanum nigrum had higher toxicity of 51.72 μg/mL. This last species had toxicity in the HeLa cell line, obtaining a 50% reduction in cell viability after 24 h; S. nigrum could be a potential anti-proliferative agent in this type of cells.