INFLUENCE OF SELECTED TRITERPENOIDS ON CHEMOPREVENTION AND THERAPY OF BREAST CANCER Minireview

Breast cancer is hormone signaling failures-related disease and the second leading cause of female cancer mortality. Among plant-based agents, triterpenoids have emerged as a promising group of phytochemicals with proposed anti-cancer activity. They are the major components of some oriental and traditional medicine herbs wildly distributed all over the world. Triterpenoids are relatively non-toxic and could be used as chemopreventive / chemoprotective agens in clinical praxis. Numerous studies using cell culture assays and animal models of cancer have revealed, that triterpenoids hold great potential not only in the therapy of breast cancer but also in preventing this disease. However, further studies are needed to explore the full potential of these agents.