Abstract 410: Isoquercetin Markedly Increases Dissection Rates in Thoracic Aortic Aneurysm Possible Structural Vasoprotection by Protein Disulfide Isomerase

Background: Thoracic aortic aneurysm and dissection (TAAD) is the outcome of biomechanical dysfunction of vascular smooth muscle cell (VSMC)-extracellular matrix (ECM) binomium. TAAD represents exa...