Growth hormone-releasing hormone: a new treatment for growth hormone deficiency

The identification and synthesis of growth hormone-releasing hormone (GHRH) coincided with the realisation that Jacob-Creutzfeldt disease could be transmitted by extracted cadaveric GH. Fortunately, the acceleration in supplies of biosynthetic GH enabled treatment regimens to be continued and even extended, and the field of growth and its therapy has since become a major focus of research. This review attempts to assess the current place of GHRH in the treatment of GH deficiency.