Detecting Direct Oral Anticoagulants in Trauma Patients using Liquid Chromatography-Mass Spectrometry: a Novel Approach to Medication Reconciliation.

Sudha Jayaraman,Jonathan H. DeAntonio,Stefan W. Leichtle,Jinfeng Han,Loren Liebrecht,Daniel Contaifer,Caroline Young,Christopher Chou,Julia Staschen,David Doan,Naren Gajenthra Kumar,Luke G. Wolfe,Tammy Nguyen,Gregory Chenault,Rahul J. Anand,Jonathan D. Bennett,Paula Ferrada,Stephanie Goldberg,Levi D. Procter,Edgar B. Rodas,Alan P. Rossi,James F. Whelan,Ventaka Ramana Feeser,Michael J. Vitto,Beth Broering,Sarah Hobgood,Martin J. Mangino,Michel B. Aboutanos,Lorin M. Bachmann,Dayanjan S. Wijesinghe

Detecting Direct Oral Anticoagulants in Trauma Patients using Liquid Chromatography-Mass Spectrometry: a Novel Approach to Medication Reconciliation.

2019

BackgroundAccurate medication reconciliation in trauma patients is essential but difficult. Currently there is no established clinical method of detecting direct oral anticoagulants (DOACs) in trauma patients. We hypothesized that a liquid chromatography-mass spectrometry (LCMS) based assay can be u

Keywords:

Medicine
Liquid chromatography–mass spectrometry
Intensive care medicine
Medication Reconciliation
Positive predicative value
clinical method
Rivaroxaban
Apixaban
Trauma center
Dabigatran
Internal medicine
Surgery

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