Antibacterial, antifungal and anti-inflammatory activities of Melia azedarach ethanolic leaf extract

The aim of the present study is to examine the antibacterial, antifungal and anti-inflammatory activities of the ethanolic leaf extract of Melia azedarach . It was tested in vitro for its antibacterial and antifungal activities against E. coli (ATCC 8739), Enterococcus faecalis (Ec P07) and Bacillus subtilis (Bs) bacteria as well as against pathogenic fungi ( Alternaria alternate , Fusarium solani, Fusarium oxysporum sp. melonis, F. oxysporum f. sp. lycopersici , F. sambucinum and Botrytis cinerea ) with different techniques similtaneously with anti-inflammatory activity with carageaneen method. All tested concentrations of M. azedarach extract showed significant antibacterial and antifungal activities with low IC 50 compared to ethanol 95% and a high anti-inflammatory activity compared with indomethacin as drug. Our investigation pointed that M. azedarach could be considered as a good medicinal agent. Video Clip of Methodology: Anti-inflammatory effect: 3 min 03 sec Full Screen Alternate