A New Synthesis of 8-Hydroxy-2-di-n-propylamino-tetralin (8-OH-DPAT)
1992
Abstract A new synthesis method for 8-OH-DPAT, a specific agonist at the 5-HT1A serotonin receptor, is described. It employs the Curtius degradation of a tetralin carboxylic acid easily prepared from (2-methoxy benzyl) succinic acid by Friedel-Crafts cyclisation.
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