THREE NEW VARIANTS OF THE α1-GLOBIN GENE WITHOUT CLINICAL OR HEMATOLOGIC EFFECTS: Hb HAGERSTOWN [α44(CE2)Pro→Ala (α1)]; Hb BUFFALO [α89(FG1)His→Gln (α1)], A HEMOGLOBIN VARIANT FROM SOMALIA AND YEMEN; Hb WICHITA [α95(G2)Pro→Gln (α1)]; AND A SECOND, UNRELATED, CASE OF Hb ROUBAIX [α55(E4)Val→Leu (α1)]

James D. Hoyer,Daniel J. McCormick,Karen Snow,Jack Lawler,Melissa Jadick,Renee Grageda,James L. Early,Carol Ball,Paula Skarda,Kathleen S. Kubik,Michael W. Holmes,Virgil F. Fairbanks

THREE NEW VARIANTS OF THE α1-GLOBIN GENE WITHOUT CLINICAL OR HEMATOLOGIC EFFECTS: Hb HAGERSTOWN [α44(CE2)Pro→Ala (α1)]; Hb BUFFALO [α89(FG1)His→Gln (α1)], A HEMOGLOBIN VARIANT FROM SOMALIA AND YEMEN; Hb WICHITA [α95(G2)Pro→Gln (α1)]; AND A SECOND, UNRELATED, CASE OF Hb ROUBAIX [α55(E4)Val→Leu (α1)]

2002

James D. Hoyer
Daniel J. McCormick
Karen Snow
Jack Lawler
Melissa Jadick
Renee Grageda
James L. Early
Carol Ball
Paula Skarda
Kathleen S. Kubik
Michael W. Holmes
Virgil F. Fairbanks

We report preliminary data for three previously unrecognized hemoglobin (Hb) variants due to mutations of the α1-globin gene, that were initially ascertained by either chromatographic, electrophore...

Keywords:

Genetics
Molecular biology
A hemoglobin
Globin
Gene
Biology
Hb Buffalo
globin gene

Correction
Source
Cite
Save
Machine Reading By IdeaReader

References

Citations