Chalcones from the flowers of Coreopsis lanceolata and their in vitro antioxidative activity.
2013
Three new chalcones, 3,2′-dihydroxy-4,3′-dimethoxychalcone-4′-glucoside
( 1 ),
4′- O -(2′′′- O -caffeoyl)2′,3′,3,4-tetrahydroxychalcone
( 2 ), and 2′,4′,3-trihydroxy-3′,4-dimethoxychalcone ( 3 ), along
with five known phenolics, were isolated from Coreopsis lanceolata flowers. The structures of the new compounds were elucidated by extensive
spectroscopic methods including NMR and MS. The three new chalcones showed a
good in vitro HepG2 cell protecting effect against
tert -butylhydroperoxide-induced oxidative stress.
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