The effects of chronic subcutaneous administration of an investigational kisspeptin analog, TAK-683, on gonadotropin-releasing hormone pulse generator activity in goats.

Takashi Yamamura,Yoshihiro Wakabayashi,Kohei Sakamoto,Hisanori Matsui,Masami Kusaka,Tomomi Tanaka,Satoshi Ohkura,Hiroaki Okamura

The effects of chronic subcutaneous administration of an investigational kisspeptin analog, TAK-683, on gonadotropin-releasing hormone pulse generator activity in goats.

2014

Takashi Yamamura
Yoshihiro Wakabayashi
Kohei Sakamoto
Hisanori Matsui
Masami Kusaka
Tomomi Tanaka
Satoshi Ohkura
Hiroaki Okamura

The continuous activation of the kisspeptin receptor by its agonists causes the abrogation of kisspeptin signaling, leading to decreased pulsatile luteinizing hormone (LH) secretion. Employing this ph

Keywords:

Gonadotropin-releasing hormone
Kisspeptin
Internal medicine
Endocrinology
Receptor
Luteinizing hormone
Biology
Secretion
Diabetes mellitus
Pulsatile flow

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