TomoTherapy total skin treatment for mycosis fungoides

2014 
An illustration of the planned, measured, and difference in leaf open times obtained during IMRT QA using the exit detector is shown to the right. The mean and standard deviation difference (relative to the projection time) was -0.54% ± 1.83%, while 97.2% of the leaf events yielded errors less than 5%. When comparing the reconstructed dose to the original plan, the mean dose difference was -0.72%, while 99.8% of the dose voxels yielded a global gamma value less than one using 3%/3 mm criteria. Only voxels whose planned dose was less than 20% of the maximum dose were included in analysis. A total of 46 TLDs were processed from the patient’s first treatment and compared to the planned dose using the calibration TLD readings. The measured dose ranged from 122.4 cGy to 192.1 cGy, with a mean and standard deviation of 154.2 ± 14.4 cGy. When compared to the planned dose, the differences ranged from -15.2% to 11.8%, with a mean and standard deviation of -0.8% ± 5.5%. A histogram of differences is provided. When comparing the TLD measurements obtained from the patient’s anterior (N=26) and posterior (N=19), no statistical significance was found in either the distribution of measured doses (p = 0.921) or dose differences (p = 0.930).
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