FIMASARTAN, AN ANGIOTENSIN II RECEPTOR ANTAGONIST, AMELIORATES AN IN VIVO ZEBRAFISH MODEL OF HEART FAILURE

Objective:Angiotensin II in the failing heart initially helps to maintain cardiac output and blood pressure, but ultimately accelerates its deterioration. In this study, we established an arrhythmia-induced heart failure (HF) model in zebrafish and investigated the role of renin-angiotensin-aldoster