withanolides type compounds and their use

The invention relates to a compound and use thereof, particularly discloses a withanolides type compound and use thereof, and belongs to the technical field of chemistry. The invention discloses two novel withanolides compounds and anti-tumor use thereof, and belongs to the field of natural pharmaceutical chemistry. Compounds I and II are reported for the first time, and can both be separated and purified from dry aboveground parts of physalis angulata L.. In-vitro activity tests show that the compounds I and II can be used for remarkably suppressing growth of human osteosarcoma cells and human hepatoma carcinoma cells and can be researched and developed into a medicament for treating human osteosarcoma and human hepatoma carcinoma.