Regulation of Kir4.1 expression in astrocytes and astrocytic tumors: a role for interleukin-1 β
2012
Objective
Decreased expression of inwardly rectifying potassium (Kir) channels in astrocytes and glioma cells may contribute to impaired K+ buffering and increased propensity for seizures. Here, we evaluated the potential effect of inflammatory molecules, such as interleukin-1β (IL-1β) on Kir4.1 mRNA and protein expression.
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