СИНТЕЗ И ФИЗИКО-ХИМИЧЕСКИЕ СВОЙСТВА ВОДОРАСТВОРИМЫХ ПРОИЗВОДНЫХ 3-БЕНЗИЛКСАНТИНА

Aim. One of the main ways of new biologically active substances search with low toxicity is synthesis of water-soluble compounds. So we developed synthesis methodic of new water-soluble 3-benzyl-8-methylxanthinides-7 by interaction of 3-benzyl-8-methylxanthine with bases in aqueous or aqueous-alcoholic medium.Methods and results. Universal method of obtaining 3-benzyl-8-methylxanthinyl-7-acetic acid, its amide and water-soluble salts has been developed. Also, as example, we offered alternative method of synthesis of 3-benzyl-8-methylxanthinyl-7-acetic acid’s esters. The structure and individuality of synthesized compounds has been proved due by elemental analysis, IR-, 1H NMR-spectroscopy and thin-layer chromatography.