Sacrum osteosarcoma after pelvic radiation for uterine cervical cancer: highlighted issues Osteossarcoma do sacro após irradiação pélvica para carcinoma do colo do útero: questões de destaque

INTRODUCTION Osteosarcoma is a rare but serious sequel of radiotherapy.1 The incidence of sarcomas post-irradiation therapy comprises about 0.1% of all cancer cases and the sarcomas usually appear 10 to 14.3 years post-treatment.1,2 Women are expected to suffer these sequels because they are more frequently subjected to radiotherapy for breast and gynecological cancers and they have better long-term survival.2 Here, the difficulties of clinical management will be briefly addressed and also some issues in the literature on this field will be discussed.