Evaluation of hypothermic activity of preparations with local anaesthesia activity according to contactless IR-thermometry data

The aim of the study is to evaluate the hypothermic activity of local anesthetic drugs as a means of choosing the prevention of post-injection complications in patients with chronic recurrent herpes. Materials and methods. Preparations based on 10% lidocaine, 20% benzocaine and chelate germanium-organic compound were used. Infrared thermometer was used to measure the temperature of the oral mucous membrane before application, immediately after 1, 2 and 5 minutes after the application of the gel, as well as to measure blood pressure. Results. When comparing the germanium chelate compound and 20% benzocaine-based gel, the significance level data showed no statistical difference (p=0.2), which indicates the possibility of choosing both drugs for clinical practice. At a lower initial temperature in hypotonics, the normo- and hypertension patients have an incomplete recovery of temperature in 5 minutes after the application of the gel. The gel based on the chelate complex of germanium-organic compound with guanine has the greatest hypothermic effect. Local hypothermia has shown high efficacy without complications in the form of relapse of chronic recurrent herpes. Conclusions. Gel based on germanium-organic chelate compound in the form of applications can be used to prevent recurrence of chronic recurrent herpes. Hypo-thermal properties of gel of germanium-organic chelate compound are recommended to be used both together with application anesthetic and isolated from it, which expands indications for its application.