Algemene vacinatie tegen meningokokken C en pneumokokken; samenvatting van het advies van de gezondheidsraad.

- The Health Council of the Netherlands (Gezondheidsraad) assessed the vaccination of infants against both group-C meningococci and pneumococci in terms of general criteria and basic principles for inclusion in the national vaccination programme. - Vaccination against meningococci C in the Netherlands is expected to prevent about 300 cases of meningococcal disease (meningitis or sepsis). 22 deaths and 12 cases of severe lasting problems (neurological problems or amputations) per year. - Vaccination against pneumococci may prevent about I00 cases of meningitis or sepsis, 3200 cases of pneumonias, 36,000 cases of acute otitis media, II deaths, II cases of severe permanent damage (neurological problems, deafness) per year. - The Health Council advised implementing vaccination against group-C meningococci as soon as possible, through 2 injections at the ages of 5 and 6 months or through I injection shortly after the child's first birthday, and to carry out a catch-up programme for all children and adolescents up to and including 18 years of age. - The council also advised starting a vaccination programme against pneumococci, at ages 2. 3 and 4 months, as soon as the current vaccinations against diphtheria, tetanus, pertussis and polio and against Haemophilus influenzae type b are combined into I injection (in 2002 or 2003). In view of the concentration of pneumococci disease in the first years of life, a catch-up programme is not indicated in this case. - The Health Council emphasised the importance of microbiological and clinical monitoring of potential adverse effects and of public education programmes. - The cost of vaccination against group-C meningococci is comparable to that of other accepted programmes for primary prevention. Compared to other programmes and at the current vaccine price, the cost of vaccination against pneumococci is high.