[Sero-epidemiological investigation on hepatitis B among permanent residents in Shenzhen area].

Objective To understand the infection status and epidemiological features of HBV in permanent residents of Shenzhen city.Methods A multi-stage stratified random sampling method was performed for questionnaire survey to permanently-registered residents of 1-59 years old in Luohu and Baoan district of Shenzhen in 2010,and blood samples of the subjects were collected.Hepatitis B virus-related surface antigen (HBsAg) and hepatitis B virus surface antibody (anti-HBs)were detected with ELISA.Results The total 3771 studied population showed 252 HBsAg positive and 2712 anfi-HBs positive residents with the standardization prevalence as 9.73％ and 72.83％,respectively.The difference of the prevalence of HBsAg and anti-HBs between males and females were not statistically significant (P＞ 0.05).The prevalence of HBsAg was reduced with increasing age.The differences of the prevalence of HBsAg between Shenzhen permanent registered and non-permanent registered population were not significant,but the prevalence of anti-HBs in Permanent registered residents (78.32％) was higher than in non-permanent (66.03％,x2 =41.613,P＜0.001).The prevalence of HBsAg was significantly different in various occupational and educational levels.Peasants had the highest prevalence (24.13％)and medical workers had the highest prevalence of anti-HBs (89.10％).People with junior high school education had the highest prevalence of HBsAg (12.76％) and the lowest of anti-HBs (62.45％).Population with high-level education had the highest prevalence of anti-HBs (81.00％ average).The prevalence of HBsAg was over 10％ in people who were born in Shenzhen and Guangdong province,and the anti-HBs was the highest in Shenzhen population with the prevalence as 74.48％ and 76.47％,respectively.Conclusion In the Shenzhen resident population,the overall prevalence of HBV was lower than the average level of Guangdong province,but higher than the national wide. Key words: Hepatitis B;  Epidemiology