The Study of β HCG Level Along With General Biochemical Profile in Pre-eclampsia

Objective-Preeclampsia is one of the leading cause of maternal mortality and morbidity worldwide. The purpose of this study was to determine the level of β hCG and other biochemical markers in preeclampsia and in normotensive patients . Method – This was a prospective study conducted on 50 preeclamptic (case)and 50 normotensive pregnant women (control) in obstetrics and gynaecology department of M.Y. hospital. Level of β hcg and other biochemical markers between case and control was compared with chi-square test. P-value <0.05 was considered significant. Result- In our study mean β hcg level in preeclamptic women( 27,802.51mIU/L ) was higher than normotensive pregnant women (12, 551.08mIU/L) with p-value<.05. Level of other biochemical markers triglycerides, total cholesterol were also higher in preeclamptic women compared to normotensive pregnant women with p-value <0.05. Conclusion- The result of this study show that level of β hcg is significantly higher in preeclampsia then in normotensive pregnant women. Level of triglyceride and total cholesterol also have significant difference in both group with higher level in preeclampsia.