IN VITRO ASSESSMENT OF ANTIBACTERIAL AND ANTIOXIDANT ACTIVITIES OF FRUIT RIND EXTRACTS OF GARCINIA CAMBOGIA. L.

Background: Garcinia cambogia is a native species of Asia and Indonesia and it is widely distributed in the subtropical region. The plant is well known for its weight reducing property especially in controlling obesity. In the present we have studied the antioxidant and antibacterial activity of G. cambogia. Materials and method: Fruit rind was dried and extracted in four different solvents (hexane, ethyl acetate, ethanol and hydro-alcoholic extracts). Each extract was individually screened for its activity against different human bacterial pathogens by agar well diffusion method. The in vitro antioxidant assay of the four different extracts of G. cambogia was also evaluated and compared to check the extract showing highest activity. Results: The ethyl acetate extract of G. cambogia exhibited better antibacterial activity where as hexane extract showed on activity against any of the test pathogens. Antioxidant assay conclude that the hydro-alcoholic extract of G. cambogia possesses the highest antioxidant activity followed by ethanol, and with hexane having no or least activity. Conclusion: The results indicate that the fruit rind extract of the plant has an excellent antibacterial activity and antioxidant property.