HIV-1 viral protein R downregulates Ebp1 and stabilizes p53 in glioblastoma U87MG cells
2014
Purpose
HIV-1 viral protein R (Vpr) inhibits cell growth and induces apoptosis in a wide range of cancers. However, the mechanism by which Vpr induces cell cycle arrest and apoptosis in GBM cell lines is unclear. The present work was taken to detect the proteins interacted with Vpr in U87MG cells.
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