Role of diet on non-alcoholic fatty liver disease： An updatednarrative review

The purpose of this article review is to update whatis known about the role of diet on non-alcoholic fattyliver disease （NAFLD）. NAFLD is the most commoncause of chronic liver disease in the developed worldand is considered to be a spectrum, ranging from fattyinfiltration of the liver alone （steatosis）, which may leadto fatty infiltration with inflammation known as nonalcoholic steatohepatitis While the majority of individualswith risk factors like obesity and insulin resistance havesteatosis, only few people may develop steatohepatitis.Current treatment relies on weight loss and exercise,although various insulin-sensitizing medications appearpromising. Weight loss alone by dietary changeshas been shown to lead to histological improvementin fatty liver making nutrition therapy to become acornerstone of treatment for NAFLD. Supplementationof vitamin E, C and omega 3 fatty acids are underconsideration with some conflicting data. Moreover,research has been showed that saturated fat, trans-fattyacid, carbohydrate, and simple sugars （fructose andsucrose） may play significant role in the intrahepatic fataccumulation. However, true associations with specificnutrients yet to be clarified.