Anti-inflammatory action of exercise training

Inflammatory reaction, like a double-edged sword, is one of the most important defense mechanisms of the organism, but in the meanwhile it leads to tissue and organ injury.Growing evidence has indicated that inflammation not only plays a key role in the onset and progression of many diseases, but is the basic pathological process in atherosclerosis, chronic heart failure, Alzheimer disease and type 2 diabetes, etc.In recent years anti-inflammatory therapy on these diseases has been a research hotpot, and exercise, as a safe and easy-to-accomplished way, has been paid more and more attention on its anti-inflammatory action.In this review we will discuss the inhibitory effect of exercise training on inflammation in atherosclerosis, Alzheimer disease and fibrosis and underlying mechanisms. Key words: Inflammation; Exercise therapy