1245 Longitudinal Follow Up in a Cohort of ELBW/VLBW Infants in the Context of the Bayley-Iii Standardization in Greece

Background It is not clear whether the Bayley III is overestimating cognitive performance or it is a more valid assessment of emerging cognitive skills than the older edition II(Vohr B 2012). Aim To compare the developmental profile in a cohort of premature infants in two different time points in order to assess the stability of the results, in the context of the Bayley-III standardization in Greece. Methods Bayley-III scales(cognitive, language, motor, social-emotional, and adaptive behavior), were administered in 103 preterm infants (≤32 weeks) at a mean age of 12mo and 24mo. Infants were divided in 2 groups based to their GA: A(n=48, 24–28wks), B(n=55, 29–32wks). All developmental assessments(206) were applied by one researcher. Results Mean(SD) Bayley-III composite scores (CSs) percentile ranks, and overall neurodevelopmental impairment (NDI 24mo) (%) for the 2 groups are shown in the table; there were no differences in CSs in any Bayley III domain in and between groups. Although not significant, ELBW showed a decrease and VLBW an increase in CSs over time. The only difference between groups was in the motor domain regarding percentile ranks and overall NDI rates(table). A significant correlation was found between: 12 th mo neuroexam with all the Bayleys subscales (p Conclusion In our cohort Bayleys III composite scores seems to be stable in serial examinations; however are lower to those reported. ELBW infants at 24mo showed a delay in the motor domain. Comparison with a control group is deemed necessary.