Effects of Subchronic Exposure to LASSO MTX® (Alachlor 42% W/V) on Hematological Indices and Histology of the Common Carp, Cyprinus carpio L.

2008 
The aim of the study was to evaluate subchronic toxic effects of the preparation LASSO MTX (alachlor 42% W/V) on hematological indices and histology of the common carp (Cyprinus carpio L.). In carp exposed for 28 days to LASSO MTX in the concentration of 2,400 μg L−1, significant differences (p < 0.05), were detected in all indices of the erythrocyte profiles tested except hematocrit (PCV) when compared to controls. At a lower exposure (240 μg L−1) concentration of blood hemoglobin and mean corpuscular hemoglobin were significantly reduced. In contrast, no influence of the preparation on leucopoiesis was demonstrated, and only slight changes were observed in histopathological indices.
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