CTX1 is A Better Index to Evaluate The Severity of Osteoporosis then Radiographic Index

Objective: To illustrate that CTX1 is the far better tool to evaluate the severity of osteoporosis then radiographic index (Singh index) in perimenopausal women. Material and Methods: This descriptive cross sectional study was done on 100 subjects, in the tertiary referral health care facilities of Peshawar via PGMI Hayatabad Medical Complex, Peshawar, Pakistan. The study was done in six months’ time period. Levels of CTX1 as a marker of bone degradation in radiographically assessed perimenopausal women were determined. These females were randomly selected and screened for osteoporosis. Radiographic grade of osteoporosis according to Singh index as 1-6 and CTX 1 level in pg/ml was taken. Results: High levels of CTX1 were observed in perimenopausal osteoporotic women, which were radiographically normal.  Conclusion: The results of this study propose that CTX1 levels are the more reliable tool for assessing osteoporosis as compared to radiographic index.