Rationally Used Antidotes in Organophosphorus Poisoning

A retrospective study was conducted at Katihar Medical College and Hospital, Bihar between July 2014-August 2015 to evaluate the utilization of two antidotes, atropine and pralidoxime, in organophosphorus poisoning (OPP). This study was carried out with data from prescription record sheet of OPP patients. Data was statistically analyzed in respect of demographic profile, signs of atropinisation and the health outcome after treatment with the antidotes. Demographic profile of 92 OPP cases between July 2014-August 2015 revealed 100% suicidal tendency, 68.48% female, 45.65% in age group of 20–30 years and 79.34% from rural population. Following stomach wash, 9.78% patients improved; rest 90.22% received antidotes (atropine to all and pralidoxime to 59.04% cases). 40.96% patient got cured after treatment with atropine only and 45.78% cured after pralidoxime addition; rest got referred to the higher center.