Действие бациллярных протеиназ на матриксные металлопротеиназы разных клеточных линий

It was investigated the effect of secreted proteinases Bacillus pumilus 7P belonging to different classes of proteolytic proteins on matrix metalloproteinases of mouse fibroblast (3T3BalbSV40), multipotent mesenchymal stromal and cells Hela-M. Matrix metalloproteinases of all cell lines was inactivated by glutamyl-specific endopeptidase. Subtilisin-like proteinase and adams-like metalloproteinase of B. pumilus did not change the activity of matrix metalloproteinases of differentcell lines.