Phytochemical Constituents of Schizonepeta tenuifolia Briquet

Column chromatographic separation of the MeOH extract from the aerial parts of Schizonepeta tenuifolia Briquet led to the isolation of twelve terpenes (1 - 11 and 17), four phenolics (13 - 16) and a hexenyl glucoside (12). Their structures were determined by spectroscopic means to be (-)-pulegone (1), piperitenone (2), p-cymene-3,8-diol (3), schizonepetoside A (4), schizonepetoside C (5), (+)-spatulenol (6), ursolic acid (7), ,,,-trihydroxyolean-12en-28oic acid (8), ,-epidioxyergosta-6,22-diol--ol (9), stigmast-4-en-3-one (10), (11), (Z)-3-hexenyl-1-O--D-glucopyranoside (12), rosmarinic acid (13), apigenin-7-O--D-glucopyranoside (14), luteolin-7-O--D-glucuronopyranoside (15), hesperidin (16) and trans-phytol (17). Compounds 2, 3, 8, 9 and 12 were for the first time isolated from S. tenuifolia Briq.