Oxazolidinone derivative, and preparation method and application thereof

The present invention relates to oxazolidinone derivatives and their preparation methods and applications, substituted oxazolidinone group of a compound represented by the general structure belongs to the field of pharmaceutical chemistry. DETAILED substituted oxazolidinone of general formula I represented by compounds, wherein, Rl represents a chlorine, bromine, methyl or trifluoromethyl; R2 represents a straight-chain or branched C1-10 saturated or unsaturated chain alkylene group chain. The compound or a pharmaceutically acceptable salt thereof as a direct factor Xa inhibitor, as antithrombotic agents, for the treatment of cardiovascular and cerebrovascular diseases and thromboembolic diseases. Formula I