Imunopatogênese da psoríase

A psoriase e doenca inflamatoria comum, afetando cerca de 1 por cento da populacao brasileira. Os linfocito T auxiliares (Th17 e Th1) estao envolvidos na imunopatogenese da psoriase. Neste artigo e discutida a interacao entre a imunidade inata (especialmente celulas dendriticas e queratinocitos) e adquirida (linfocitos T) na patogenese da psoriase. Psoriasis is a common inflammatory disease affecting 1 percent of the Brazilian population. Th17 and Th1cells are involved with the immunopathogenisis of psoriasis. In this article it is discussed the interaction between the innate immunity (especially dendritic cells and keratinocytes) and adaptive immunity (T lymphocytes) in the pathogenesis of psoriasis.