Screening of BRCA2 mutated men for detection of prostate cancer: Preliminary results from a national high volume cancer center.

e16567Background: Up to 10% of cases of Prostate Cancer (PCa) are hereditary. Germline pathogenic mutations in BRCA2 gene confer the highest risk (2.5 to 8.6 fold in men ≤ 65 yr). Beyond periodic P...