SYNTHESIS OF THREE ((TRIFLUOROETHYL)AMINO)PYRIDINES

The synthesis of o-, m, and p-((trifluoroethyl)amino)pyridine by diborane/tetrahydrofuran reduction of the corresponding trifluoroacetamide is described. The yields were 52%, 83%, and 76%, respectively. The synthesis, in 53% yield, of 2,2,2-trifluoro-N-(4-pyridyl)acetamide is also described.