Treatment of Pain Associated with Lyme Disease Neuralgia Using Perineural Injection Therapy: A Case Report

1. Abstract This case report demonstrates a novel and successful treatment for induced pain associated with Lyme disease. Perineural Injection Therapy was used as the sole treatment for neurological pain in the hand, knee, leg, and foot of the patient. Conventional treatment for Lyme neuralgia often focuses on the use of pharmaceutical agents such as tricyclic antidepressants and gabapentin which do not focus on decreasing the inflammation of the nerves associated with Lyme disease. The patient received five injection treatments for the left-hand pain and nine injection treatments for the right knee, leg and foot pain that successfully decreased the pain by 80% and increased joint mobility that led to an increased quality of life as reported by the patient. The treatment was not only successful in providing immediate decrease in pain but also had a long-lasting effect with minimal side effects. As the pain did not return once the treatment was completed, therefore, the study supports the use of Perineural Injection Therapy as a novel and successful treatment for addressing Lyme neuralgia. 2. Keywords: Borrelia burgdorferi ; Chronic lyme disease; Chronic pain; Lyme disease; Lyme neuralgia; Neural prolotherapy; Naturopathic medicine; Neuroborreliosis; Perineural injection therapy