DNA Double-Strand Break Repair Genes and Oxidative Damage in Brain Metastasis of Breast Cancer

Stephan Woditschka,Lynda M. Evans,Renata Duchnowska,L. Tiffany Reed,Diane Palmieri,Yongzhen Qian,Sunil Badve,George W. Sledge,Brunilde Gril,Mirit I. Aladjem,Haiqing Fu,Natasha M. Flores,Yesim Gökmen-Polar,Wojciech Biernat,Ewa Szutowicz-Zielińska,Tomasz Mandat,Tomasz Trojanowski,Waldemar Och,Bogumiła Czartoryska-Arłukowicz,Jacek Jassem,James B. Mitchell,Patricia S. Steeg

DNA Double-Strand Break Repair Genes and Oxidative Damage in Brain Metastasis of Breast Cancer

2014

Background Breast cancer frequently metastasizes to the brain, colonizing a neuro-inflammatory microenvironment. The molecular pathways facilitating this colonization remain poorly understood.

Keywords:

Brain metastasis
BARD1 Gene
Breast cancer
DNA
Immunology
Gene
Double Strand Break Repair
DNA repair
Oxidative stress
Biology

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