[Toxicity of 50% ethanol salt powder of niclosamide on growth of silkworms].

OBJECTIVE: To observe the toxity of niclosamide on the growth of silkworms. METHODS: Mulberry leaves were soaked in the different concentrations of solution of 50% ethanol salt powder of niclosamide for 10 s or 3 min, and then the leaves were fed to silkworms. The death rates of silkworms and the weight of cocoons were observed. Normal feeding control groups were established. RESULTS: The death rates were 22.5%-85.0% and 56.0%-100% in the 10-s-soaked groups and 3-min groups, respectively, which were significantly higher than those in the control groups. CONCLUSION: The 50% ethanol salt powder of niclosamide has a toxity for silkworm. Therefore, we should properly handle the relationship between the Oncomelania snail control and silkworm breeding.