Recognizing seromadesis to prevent false-positive PET-CT interpretations.

e22084 Background: Seromas are the result of a local inflammatory response to a mechanical injury incurred by tissue aggression either during surgery or the presence of foreign bodies. Unfortunately, the common practice of using of percutaneous or surgical drains, does not decrease the frequency of seroma formation and is associated with an increased risk of infection. Methods: Since first introduced in 1935 for pleurodesis, talcum powder has been used extensively as a simple, effective, and economic procedure for the treatment and prophylaxis of recurrent pleural effusions. It induces a strong fibrotic reaction due to the activation of polymorphonuclear neutrophils, interleukin 8 and fibroblast growth factor. One of the earliest documented uses was by Coons et al., in 1993 utilizing an experimental dog model. In 2006, Saeb-Parsy et al. described its use in recurrent seroma after breast surgery. More recently in 2012, Klima et al. reported that a prophylactic application of subcutaneous talc after axillar...