Reacciones psoriasiformes paradójicas secundarias a terapias biológicas con anti-TNF-alfa

As a consequence of the advance in different medical treatments, like with the use of biologic drugs such as anti-TNF-alpha, there can be seen paradoxical psoriasiform reactions. The paradoxical reactions consist of the exacerbation or the appearance of a new symptom or another disease that, generally, improve with the use of biological agents such as anti-TNF-alpha, drugs have several indications related to the treatment of different inflammatory pathologies, hence, it is crucial that every specialist who prescribes them are aware of this secondary effect. The aim of this article was to observe and describe the demographic and clinical characteristics of a group of patients with paradoxical psoriasiform reactions; and to compare them with the literature.