Stage specific health utility index scores of Canadian cancer patients.

6614 Background: In order to improve the precision of health economics analyses in oncology, reference datasets of health utility index (HUI) scores are needed from cancer patients. These data are particularly sparse among Canadian patients. Using EQ5D we generated stage-specific HUI scores for lung, breast, colorectal, prostate, head/ neck and ovarian cancer, and all-stage reference values for 21 additional cancer sites. Methods: 1,760 ambulatory cancer patients at the Princess Margaret completed the EQ5D instrument. HUI scores were calculated using Canadian valuations. Clinical information was abstracted from patient charts and data was analyzed using descriptive statistics and multiple regression. Results: Among all patients, the mean±SEM HUI score was 0.81±0.004 (Canadian algorithm). The cancer sites with the lowest mean HUI scores were acute lymphoblastic leukemia (0.70±0.03) and pancreatic (0.76±0.03); testicular (0.89±0.02) and chronic lymphocytic leukemia (0.90±0.05) had the highest scores. Scores...