SYNTHESIS OF BIOTIN AND 1′-METHYLBIOTIN

S. I. Zav'yalov,N.A. Rodionova,L. L. Zheleznaya,G. I. Bolestova,V V Filippov,Z.N. Parnes,D. N. Kursanov

SYNTHESIS OF BIOTIN AND 1′-METHYLBIOTIN

1975

S. I. Zav'yalov
N.A. Rodionova
L. L. Zheleznaya
G. I. Bolestova
V V Filippov
Z.N. Parnes
D. N. Kursanov

2,3,4,5-Tetradehydrobiotin and its 1′-methyl derivative undergo ionic hydrogenation with triethylsilane in trifluoroacetic acid to respectively give biotin and 1′-methylbiotin.

Keywords:

Organic chemistry
Chemistry
Biotin

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