Method for quality detection of monkshood-radix glycyrrhizae medicament

2015 
The invention provides a method for the quality detection of a monkshood-radix glycyrrhizae medicament. The method is characterized in that a chromatographic column taking a polar diethyl ether connected phenyl bonded silica gel as a filler is adopted for identifying and determining the content of monkshood, so that the separating degree, peak shape and tailing factor of a target component are significantly improved; a thin-layer chromatography is adopted for identifying radix glycyrrhizae; high performance liquid chromatography is adopted for controlling the content of diester-type alkaloids; and related methodology validation and example inspection show that according to the method provided by the invention, the monkshood-radix glycyrrhizae medicament can be simply and accurately identified, the content of diester-type alkaloids can be controlled, and the contents of monkshood and radix glycyrrhizae can be detected, so that the product quality can be effectively guaranteed in the processes of production and use, and then the curative effect of the medicament is ensured.
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