Cutaneous aspergillosis in a boy with acute leukemia: the lessons from a “simple” case

Fungal infections are among the most serious infectious complications in immunosuppressed patients. Primary cutaneous aspergillosis is a relatively rare manifestation and is usually described in patients with underlying malignant hematological diseases, AIDS, allogenic stem cell transplantation, solid organ transplantation, etc. We present a clinical case of a 12-year-old boy with acute lymphoblastic leukemia initially diagnosed as primary cutaneous aspergillosis caused by Aspergillus flavus . The retrospective analysis demonstrates that a small solitary pulmonary nodule could be a possible portal of entry. This means that we could consider the disease as an early stage invasive aspergillosis, which is successfully treated with voriconazole.