The impact of physical exercise on calcium balance in healthy subjects during prolonged hypokinesia.

Abstract Objective To determine whether during hypokinesia (diminished movement) periodic physical exercise affects calcium (Ca 2+ ) balance and Ca 2+ loss. Methods Studies were conducted on 30 physically healthy male volunteers during the preexperimental period of 30 days and the experimental period of 364 days. They were equally divided into three groups: active control subjects (ACS), hypokinetic subjects (HKS), and periodic training subjects (PTS). The ACS group ran an average distance of 9.3 ± 1.2 km/d; the HKS group walked an average distance of 1.3 ± 0.2 km/d; and PTS group walked and ran average distances of 1.3 ± 0.2 km/d and 9.2 ± 1.2 km/d for 5 and 2 days per week, respectively. Results Serum Ca 2+ level, fecal and urine Ca 2+ loss, and Ca 2+ imbalance increased ( P 2+ concentration, urine and fecal Ca 2+ loss, and Ca 2+ imbalance increased more ( P Conclusion During hypokinesia, Ca 2+ imbalance is more evident with than without physical exercise and Ca 2+ loss is exacerbated more with higher than lower Ca 2+ imbalance.