Role of combined polymorphisms of SLCO1B1 and CYP2C9 on blood glucose-lowering effect of nateglinide

2010 
目的:研究SLO1B1 521TC变异以及SLO181 521TC和CYP2C9·3的联合突变对口服降糖药那格列奈的降血糖效果的影响.方法:对48名健康志愿者(12例SLCO181 521TT/CYP2C9·1基因型,14例SLCO1B1 521 TT/CYP2C9·3基因型,12例SLCO1B1 521TC/CC/CYP2C9·1基因型,10例SLCO1B1521TC/CYP2C9·3基因型)单...
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