Analysis of reperfusion delay in patients with acute ST elevated myocardial infarction based on gender difference

Objective 　To examine the influence of gender difference on the reperfusion delay in patients with ST-elevation myocardial infarction (STEMI). Methods 　A total of consecutive 325 patients with STEMI were analyzed admitted in the 306 Hospital of PLA from Jan. 2011 to Dec. 2015. Patients were divided into two groups: male group (n=268) and female group (n=57). The clinical data and the time intervals including symptom onset to first medical contact (So-to-FMC), transfer delay (FMC-to-D), FMC to balloon dilatation (FMC-to-B), activation delay and door to balloon (D-to-B) time were compared between different gender groups, and the prognosis was observed. Results 　The overall median of pre-hospital delay was 125 minutes. The median of pre-hospital delay time (male 119.5min vs. female 160.0min) and So-to-FMC time (male 69.5min vs. female 100.0min) were longer in female than in male patients, but no statistical difference existed (P>0.05) between the two groups in pre-hospital delay, So-to-FMC, FMC-to-B, D-to-B and total ischemia time. Compared with male patients, female patients were more likely to have additional comorbidities, such as hypertension and diabetes mellitus, and lower rate of smoking (P 0.05). Conclusion 　The influence of gender on reperfusion delay is gradually weakening. DOI: 10.11855/j.issn.0577-7402.2017.02.10