Effect of mefenamic acid and sodium salicylate on lymphocyte transformation due to phytohemagglutinin

It is established in in-vitro experiments that mefenamic acid and sodium salicylate inhibit to an equal measure the cell immunity test, a reaction of blast transformation of lymphocytes. The effect increases with the higher concentration of the drugs under study and depends on the time they are introduced into the culture with respect to the introduction of the non-specific mitotic stimulant phytohemagglutinin.